GOURDI Robert (US),ГОУРДИ Роберт (US),GKhATNEKAR Gautam (US),ГХАТНЕКАР Гаутам (US),DZhOURDAN Dzhejn (US),ДЖОУРДАН Джейн (US),GOURDI ROBERT,GKHATNEKAR GAUTAM,DZHOURDAN DZHEJN
申请号：
RU2007127888/15
公开号：
RU0002438696C2
申请日:
2005.12.20
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
FIELD: medicine, pharmaceutics.SUBSTANCE: group of inventions relates to field of medicine and deals with development of medications for acceleration of wound healing and tissue regeneration after damaging individual's tissues. Claimed is composition for acceleration of wound healing, which contains at least one polypeptide, consisting of 4-30 sequential amino acids of carboxy-end of alpha-connexin or its conservative version, where at least one said alpha-connexin polypeptide is bound on amino-end with carrier of cellular internalisation. Also claimed is composition for acceleration of tissue healing, composed for local application, containing polypeptide, which consists of 4-30 sequential amino acids of carboxy-end of alpha-connexin protein or its conservative version, and material for wound treatment for acceleration of tissue healing, covered by such polypeptide. Set for wound healing acceleration can contain mentioned above compositions or material for wound treatment and instruction for their application. Also claimed is application of mentioned above compositions and material for obtaining medicine, which accelerates tissue healing.EFFECT: application of polypeptide, which consists of 4-30 sequential amino acids of carboxy-end of alpha-connexin protein or its conservative version ensures reduction of inflammation after tissue damaging, acceleration of healing, reduction of scarring, intensification of compound tissue regeneration.31 cl, 2 tbl, 5 ex, 17 dwgГруппа изобретений относится к области медицины и касается разработки лекарственных средств для ускорения заживления ран и регенерации тканей после повреждения ткани у индивидуума. Предлагается композиция для ускорения заживления тканей, содержащая по меньшей мере один полипептид, состоящий из 4-30 последовательных аминокислот карбокси-конца белка альфа-коннексина или его консервативного варианта, где указанный по меньшей мере один полипептид альфа-коннексин связан на амино-конце с переносчиком клеточной и
