Donald Rao;F. Charles Brunicardi;John J. Nemunaitis
发明人:
John J. Nemunaitis,Donald Rao,F. Charles Brunicardi
申请号：
US13693578
公开号：
US09133459B2
申请日:
2012.12.04
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A bifunctional shRNA-based composition and methods for knocking down the expression of the PDX-1 oncogene in target cells is described herein. The invention also provides methods to deliver the shRNA-containing expression vectors to target tissues overexpressing the PDX-1 oncogene.
