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Method for preparing dry powder for inhalation formulation comprising salmeterol xinafoate, fluticasone propionate and tiotropium bromide
专利权人:
HANMI PHARM. CO.; LTD.
发明人:
Kyeong Soo Kim,Deokkyu Lee,Dong Ho Kim,Yong II Kim,Jae Hyun Park,Jong Soo Woo
申请号:
US14746225
公开号:
US09549936B2
申请日:
2015.06.22
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Disclosed are a dry powder for inhalation formulation comprising salmeterol xinafoate, fluticasone propionate and tiotropium bromide, as pharmaceutically active ingredients, and a carrier, and an inhalation formulation comprising same and a method for preparing the same. The inventive dry powder inhalation formulation having good content uniformity and showing small changes in the aerodynamic size distribution in accordance with the flow rate changes can effectively deliver said pharmaceutically active ingredients to a target site upon administration, and thus can be useful in the prevention or treatment of respiratory diseases, particularly asthma and COPD.
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