PROBLEM TO BE SOLVED: To provide a xanthine oxidase inhibitor derived from natural products, and a method for producing the same, and a pharmaceutical and a functional food containing the xanthine oxidase inhibitor as an active ingredient.SOLUTION: This invention relates to a xanthine oxidase inhibitor containing a heated product of coffeic acid, as an active ingredient; a xanthine oxidase inhibitor described above, containing a polymer of coffeic acid as an active ingredient; and a method for producing a heated product of coffeic acid by heating a solid of coffeic acid at 110-290°C.SELECTED DRAWING: NoneCOPYRIGHT: (C)2019,JPO&INPIT【課題】天然物に由来するキサンチンオキシダーゼ阻害剤及びその製造方法、並びに当該キサンチンオキシダーゼ阻害剤を有効成分とする医薬品及び機能性食品の提供。【解決手段】カフェ酸加熱物を有効成分とする、キサンチンオキシダーゼ阻害剤、カフェ酸重合体を有効成分とする、前記記載のキサンチンオキシダーゼ阻害剤、及び、固体のカフェ酸を110~290℃で加熱する、カフェ酸加熱物の製造方法。【選択図】なし