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TETRA-SUBSTITUTED NDGA DERIVATIVES VIA ETHER BONDS AND CARBAMATE BONDS AND THEIR SYNTHESIS AND PHARMACEUTICAL USE
专利权人:
发明人:
Qingqi CHEN,Rocio Alejandra LOPEZ,Jonathan Daniel HELLER,Amanda Jean MORRIS
申请号:
US14753695
公开号:
US20150374709A1
申请日:
2015.06.29
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed are nordihydroguaiarctic acid derivative compounds including various end groups bonded by a carbon atom or heteroatom though a side chain bonded to the respective hydroxy residue O groups by an ether bond or a carbamate bond, pharmaceutical compositions, methods of making them, and methods of using them and kits including them for the treatment of diseases and disorders, in particular, diseases resulting from or associated with a virus infection, such as HIV infection, HPV infection, or HSV infection, an inflammatory disease, such as various types of arthritis and inflammatory bowel diseases, a metabolic disease, such as diabetes, a vascular disease, such as hypertension and macular degeneration, or a proliferative disease, such as diverse types of cancers.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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