The invention discloses a pneumatic-electric linked switch and a medical device with the pneumatic-electric linked switch. The pneumatic-electric linked switch comprises a pneumatic valve assembly, a connecting piece, a transmission piece and a driving piece, wherein the pneumatic valve assembly comprises a valve body and a valve element, an air passage is arranged in the valve body, the valve element is arranged on the valve body in the mode that the valve element can move between a connection position where the valve element is communicated with the air passage and a disconnection position where the valve element is disconnected with the air passage, the connecting piece is arranged on the pneumatic valve assembly, the transmission piece is arranged on the connecting piece in the mode that the transmission piece can move between an opening position and a closing position and is matched with the valve element, the valve element is located at the connection position when the transmission piece is located at the opening position, the valve element is located at the disconnection position when the transmission piece is located at the closing position, and the driving piece is connected with the transmission piece so as to drive the driving piece to move between the opening position and the closing position. The pneumatic-electric linked switch has the advantages of being simple in structure, convenient to disassemble and assemble, low in manufacturing cost and the like.