UNIVERSITY OF CHICAGO;KARL-FRANZENS-UNIVERSITAT GRAZ
发明人:
BIRUKOV, KONSTANTIN,BIRUKOVA, ANNA,BOCHKOV, VALERY,OSKOLKOVA, OLGA
申请号：
CA3071476
公开号：
CA3071476A1
申请日:
2018.07.27
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present invention relates to a compound having a structure according to formula (I) or a salt thereof, wherein : R1 is a branched or linear alkyl, acyl, alkenyl, hydroxyalkyl, hydroxyalkenyl, or hydroxy-alkinyl residue comprising 6 to 30 carbon atoms, R2 is selected from the group consisting of : a) an alkyl residue comprising 1 to 10 carbon atoms and comprising a terminal or cyclic quaternary ammonium, b) an alkyl residue comprising 1 to 10 carbon atoms and comprising a terminal amino group and/or 1 to 3 hydroxyl groups, c) an amino acid residue, d) a five or six carbon sugar and e) H, R3 is a residue selected from the group consisting of an alkyl, alkenyl, prostanyl-dialkyl, furanyl-dialkyl, cyclobutyl-dialkyl, cycloalkyl and aryl group of 2 to 40 carbon atoms length and comprising at least one keto group, epoxy group, aldehyde group, peroxy group, hydroperoxy group, hydroxyl group or a free carboxyl group, L1 is selected from the group consisting of O, NH, S, CH2, (aa), (bb), (cc), (dd), (ee), (ff), (gg), (hh), (ii), (jj), (kk), (ll), (mm), or (nn), L2 is an amide group or an ether group, X and Z are independently O, S or CH2, and Y is selected from the group consisting of O and S.
