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LOW-SUBSTITUTED HYDROXYPROPYL CELLULOSE, PRODUCTION METHOD THEREOF, AND SOLID PREPARATION
专利权人:
发明人:
HIRAMA YASUYUKI,TSUCHIYA AYA
申请号:
IN201714035614
公开号:
IN201714035614A
申请日:
2017.10.06
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
Provided are low-substituted hydroxypropyl cellulose (L-HPC) having a hydroxypropoxy content of from 5 to 16% by weight, and having, on a basis of a dynamic image analysis to divide all particles into fine, spherical, and fibrous particles consisting of long and short fibrous particles, a volume fraction of the long fibrous particles of from 15 to 50% and a volume fraction of the short fibrous particles of from 23 to 60% and a solid preparation containing the L-HPC. Also provided is a method for producing the L-HPC including the steps: bringing sheet-like or chip-like pulp having a length-weighted average fiber length of from 2.40 to 3.50 mm into contact with an alkali metal hydroxide solution, reacting the resulting alkali cellulose with propylene oxide, and dispersing the resulting reaction product in water containing an acid to partially dissolve it therein, followed by neutralization with an acid to precipitate crude L-HPC.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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