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Hard Capsule Shell Compositions for the Oral Contraceptive Formulations
专利权人:
Hemant N. Joshi;Amitkumar Lad
发明人:
Hemant N. Joshi,Amitkumar Lad
申请号:
US15975270
公开号:
US20190343770A1
申请日:
2018.05.09
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A hard shell capsule includes a body and a cap cooperatively defining a hollow core hard shell capsule. Each of the body and the cap has a composition that includes a polymer forming a hard polymer structure of the body and of the cap and comprises a drug. The body further comprises a therapeutically effective amount of drug A loaded throughout the composition; the cap further comprises a composition comprising a therapeutically effective amount of drug B loaded throughout the composition. The body and cap compositions together containing a therapeutically effective amount of the drugs A and B; said drugs being oral contraceptive agents. The core of the capsule is filled with therapeutically effective amount of a second drug(s), a dietary supplement, minerals, a complexing agent and other excipients. With the help of FIG. 2, the invention can be very well understood easily. Drugs A and B are selected from the group of oral contraceptives, but are not limited to, Cyproterone acetate, Estradiol, Oestradiol, Norethindrone acetate, Ethinyl Estradiol, Levonorgestrel, Dienogest, Drospirenone, Desogestrel, Ethynodiol, Diacetate, Mestranol, Nomegestrol acetate, Norgestrel, Norgestimate, Dienogest, Norelgestromin, Norethisterone, Gestodene, Oestradiol valerate, and Ethynodiol diacetate.
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