A system includes at least one earpiece, wherein each earpiece comprises an earpiece housing, an optical source operatively connected to the earpiece housing, wherein the optical source is configured to emit light toward an ear surface, an optical sensor operatively connected to the earpiece housing, wherein the optical sensor is configured to receive reflected light from the ear surface, and at least one processor disposed within at least one earpiece and operatively connected to the optical source and the optical sensor, wherein the at least one processor is configured to separate the pulse oximetry signals from the audio signals in the reflected light detected by the optical sensor.