Campbell McInnes,Padmavathy Nandha Premnath,Joshua K. Bolger
申请号:
US15192247
公开号:
US09982015B2
申请日:
2016.06.24
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Structural and functional analysis of peptide inhibitor binding to the cyclin D and cyclin A groove has been investigated and used to design peptides that provide the basis for structure-activity relationships, have improved binding and have potential for development as chemical biology probes, as potential diagnostics and as therapeutics in the treatment of proliferative diseases including cancer and inflammation.