THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
发明人:
Steven Marx,Alexander Kushnir,Lin Yang,Alex Katchman,Henry M. Colecraft
申请号：
US16228433
公开号：
US20190250145A1
申请日:
2018.12.20
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention provides, inter alia, methods for identifying a candidate agent that can treat or ameliorate the effects of a heart condition caused by the effects of abnormal beta-adrenergic receptor activation on calcium levels in cardiomyocytes in a subject. Compositions that include the candidate agents identified by the methods disclosed, and methods of treating or ameliorating the effects of a heart condition in a subject by administering to the subject the candidate agents identified by the methods disclosed, are also provided.
