METHODS FOR TREATMENT AND PROPHYLAXIS OF HIV AND AIDS农业专利-农业学术服务平台

发明人:: HAZUDA, DARIA,哈族达达利亚,哈族達達利亞,MILLER, MICHAEL D.,米勒麦可 D,米勒麥可 D,GROBLER, JAY A.,果卜勒洁 A,果卜勒潔 A,NICOLL-GRIFFITH, DEBORAH ANNE,尼寇-古利非斯黛柏拉安,尼寇-古利非斯黛柏拉安

摘要：: The present invention is directed to methods for inhibition of HIV reverse transcriptase, treatment of infection by HIV, prophylaxis of infection by HIV, and the treatment, prophylaxis and/or delay in the onset or progression of AIDS or ARC by administering a compound of structural Formula I, or a pharmaceutically acceptable salt or co-crystal thereof, wherein X is -F or -Cl, less frequently than once daily.本發明係關於藉由低於每日投藥一次的頻率投與結構式I之化合物或其醫藥學上可接受之鹽或共晶體來抑制HIV反轉錄酶、治療HIV感染、預防HIV感染,及治療、預防及/或延遲AIDS或ARC之發作或演進的方法, 其中X為-F或-Cl。