A variety of targeting moiety peptide epitope complexes (TPECs) are described in different embodiments. In each of the embodiments however a targeting moiety may be used to deliver the TPEC to an area of unwanted cells allowing for a therapeutic effect to be delivered locally. The TPEC also contains a plurality of T cell epitopes. The TPEC further comprises cleavage sites that release the T cell epitopes from the targeting agent and in some embodiments from each other when they are in the microenvironment of the unwanted cells. Although the arrangement and number of T cell epitopes varies in different embodiments described herein once cleaved from the targeting agent (and any neighboring T cell epitopes) the T cell epitopes function by stimulating an immune response against the unwanted cells.
