The present invention provides a novel medicament or method for treatment or diagnosis of cancer.Namely, the present invention provides a substance capable of inhibiting the expression of PUF60 gene, a substance capable of inhibiting the activity of PUF60 protein and a pharmaceutical composition containing the same as active ingredient these substances and the pharmaceutical composition can be used in treatment or diagnosis of cancer.本發明提供一種用於治療或診斷癌之新穎藥劑或方法。亦即,本發明提供PUF60基因之表現抑制物質、PUF60蛋白質之活性抑制物質以及含有此等物質作為有效成分之醫藥組成物,此等物質及該醫藥組成物可用於癌之治療或預防。由於本案的圖為照片及實驗數據,並非本案的代表圖。故本案無指定代表圖。