ALLISON L., ZULLI,BRUCE D. DORSEY,CRAIG A. ZIFICSAK,DIMITAR B. GOTCHEV,LINDA WEINBERG,NADINE C. BECKNELL,REDDEPPA REDDY DANDU,ROBERT L., HUDKINS
申请号：
BR112017027339
公开号：
BR112017027339A2
申请日:
2016.06.17
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
Described herein are 1,4-substituted piperidine compounds according to Formula (I) that have demonstrated activity as fatty acid synthase inhibitors. Also described herein are pharmaceutical compositions containing the described 1,4-substituted piperidine compounds, and methods of treating diseases mediated by fatty acid synthase, by administering one or more of the compounds or pharmaceutical formulations described herein. Also described herein are methods of synthesizing the compounds described, including the described 1,4-substituted piperidine compounds and synthetic intermediates useful in those syntheses.
