GOPI M VENKATESH,CRAIG KRAMER,FLAVIO FABIANI,LUIGI MAPELLI,GIOVANNI ORTENZI,MASSIMO LATINO
申请号：
IN10092/CHENP/2012
公开号：
IN2012CN10092A
申请日:
2012.11.30
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
The present invention relates to a small particle size composition comprising pancreatin containing digestive enzymes for use in patients in need including pediatric geriatric and adult patients particularly those patients with dysphagia or wherein enteral administration using such composition would be suitable. In addition the invention is directed to the composition as particles such as micropellets or microgranules having a high potency high useable yield and at least 10% - 90% of 400-800 �m. Furthermore the composition optionally has an improved enteric coating and concomitant improved stability and enzyme activity compared to conventional prepared enterically coated pancreatic enzyme particles.
