It is intended to provide a peptide which is a candidate for a cancer vaccine for HLA-A33<;+>; cancer patients. Namely, a peptide originating in a stress-induced apoptosis-related gene (IEX-1) which is recognized by cytotoxic T lymphocyte (CTL) and capable of inducing specific CTL, its mutant peptide, a polypeptide containing the above peptide, a nucleic acid molecule encoding the same, a medicinal composition containing the same, etc.