Nogueira, Keith,Engel, Taly G.,Li, Xiaolong,Liang, Bradley C.,Shah, Rajiv,Liu, Mike C.,Tsai, Andy Y.,Kim, Jaeho,Varsavsky, Andrea,Yu, Fei,Gautham, Raghavendhar,Nishida, Jeffrey
申请号：
AU2020203049
公开号：
AU2020203049A1
申请日:
2020.05.08
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
#$%^&*AU2020203049A120200528.pdf#####ABSTRACT A method for real-time calibration of a glucose sensor for measuring a level of glucose in a body of a user, said glucose sensor including physical sensor electronics, a microcontroller, and a working electrode, the method comprising: (a) measuring, by said physical sensor electronics, an electrode current (Isig) for the working electrode； (b) obtaining ablood glucose (BG) value for said user； (c) performing, by said microcontroller, an electrochemical impedance spectroscopy (EIS) procedure for said working electrode to obtain a respective plurality of values of an impedance-based parameter for said working electrode, and expecting calibration errors based on said respective plurality ofvalues of an impedance-based parameter； (d) providing, by said microcontroller, variable calibration error thresholds based on expectation of calibration error； (e) updating, by said microcontroller, a calibration factor CF with accepted BG values based on said variable calibration error thresholds； (f) calculating, by said microcontroller, a calibrated sensor glucose (SG) value associated with said Isig based on said updated CF and accepted BG values； and (g) calculating, by said microcontroller, an amount of insulin to be delivered to said user based on said calibrated SG value.
