FORME GALENIQUE SOLIDE FORTEMENT POREUSE ET A DESINTEGRATION RAPIDE ET PROCEDE DE PRODUCTION ASSOCIE COMPORTANT LA PREPARATION D'UNE POUDRE ET UNE ETAPE DE LYOPHILISATION

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专利权人:

PANTEC AG

发明人:

BAUER, KURT HEINZ

申请号：

CA2585426

公开号：

CA2585426C

申请日:

2005.10.27

申请国别(地区):

CA

年份:

2013

代理人:

摘要：

The invention relates to a method of manufacture of fast-disintegrating soliddosage forms, characterized in that one or more structure building componentsin mixed solid powder form are dosed into cavities of blister packs or moulds,the remaining components dissolved in water dosed and added to the powder toform a moistened, plasticized mass, frozen to below -20~C , and the watersublimed in high vacuum. In this way solid dosage forms are obtainable with asimilar porous structure as usually result from freeze-drying processes, butthe process requires much less water, which means considerably less time andless energy.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/