WANG, QUN,STOVER, CHARLES K.,PENNINI, MEGHAN,CHANG, CHEW-SHUN,XIAO, XIAODONG,HILLIARD, JAMESE,KAPLAN, GILAD,CORTI, DAVIDE,CAMERONI, ELISABETTA,BELTRAMELLO, MARTINA
申请号：
CA3039686
公开号：
CA3039686A1
申请日:
2017.10.16
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present disclosure provides binding proteins (e.g., antibodies or antigen binding fragments thereof) that specifically bind to Klebsiella pneumoniae O1 and induce opsonophagocytic killing of Klebsiella (e.g., Klebsiella pneumoniae). The present disclosure also provides methods of reducing Klebsiella (e.g., Klebsiella pneumoniae) or treating or preventing Klebsiella (e.g., Klebsiella pneumoniae) infection in a subject comprising administering the Klebsiella pneumoniae O1 binding proteins, (e.g., antibodies or antigen-binding fragments thereof) to the subject.
