A vascular closure system includes a body portion, an anchor, at least one suture member, and a plurality of needles. The anchor assembly includes a hub and a wire assembly. The hub has at least one aperture defined in a sidewall thereof. The wire assembly includes an actuator member extending proximally through the body portion and hub, and at least one pre-formed wire having a free proximal end and a distal end that is connected to the actuator member. Withdrawing the actuator member extends the proximal end of the at least one pre-formed wire out of the at least one aperture to capture a portion of the vessel wall between the pre-formed wire and the body portion. The plurality of needles extend through the vessel wall adjacent to the vessel puncture and are configured to connect to the at least one suture member.
