An adhesive wafer (10) for an ostomy device, the wafer comprising a skin-facing adhesive layer (40), a backing layer (30) on the non-skin- facing side of the adhesive layer, and a hole (60) for accommodating a stoma. On the central portion of the backing layer is located a release layer (110) being configured to release a neutralizer. The neutralizer is capable of neutralizing or at least minimizing the level of skin or adhesive aggressiveness of the output.