Julia Romanova,Andrej Egorov,Brigitte Krenn,Markus Wolschek,Sabine Nakowitsch
申请号:
US13129806
公开号:
US08815252B2
申请日:
2009.11.25
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides a method for producing pH-stable enveloped viruses wherein said viruses are used for infection of host cells under low pH conditions and for incubation with cell culture cells under conditions of low pH, as well as influenza viruses obtainable by this method which exhibit a high growth rate in cell culture, increased pH and temperature stability and which have human receptor specificity.