SYNTHESE DE THAPSIGARGINE, NORTRILOBOLIDE ET LEURS ANALOGUES

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专利权人:

QUEEN'S UNIVERSITY AT KINGSTON

发明人:

EVANS, ANDREW P.,CHEN, DEZHI

申请号：

CA3057520

公开号：

CA3057520A1

申请日:

2018.03.27

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The present invention relates to the preparation of compounds of Formula I, including thapsigargin, nortrilobolide and 8-O-debutanoyl-thapsigargin from commercially available (R)-(-)-carvone via synthetic intermediate compound of formula 12 by pinacol coupling and in situ lactonization.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/