The present invention is related to a composition for relieving joint inflammation. The present invention is also related to a method for treatment of joint inflammation, comprising a step of administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition. By means of inhibiting the COX-2 and NF-&kgr；B expression through the composition or the pharmaceutical composition with specific ratio, the joint inflammation and swelling could be reduced and the osteoclasts proliferation could be decreased to mitigate bone erosion, osteoporosis and degenerative arthritis.本發明關於一種用於減輕關節炎症的組合物。本發明亦關於一種以前述組合物用於治療關節炎之用途，該用途包括將所述之有效劑量組合物施予受體；並藉由包含特定組分之白藜蘆醇、薑黃萃取物與槲黃素之組合物或醫藥品以達到抑制COX-2及NF-κB表現，進以減少蝕骨細胞增殖以及減緩骨質流失、骨質疏鬆症及退化性關節炎。
