1-ethyl-7- (2-methyl-6- (1H-1,2,4-triazol-3-yl) pyridin-3-yl) -3,4-dihydropyrazine [2,3-b] pyrazin-2 (1H) -one or a pharmaceutically acceptable salt, clathrate, solvate, stereoisomer, tautomer or isotopologist thereof for use in a method of treating Ewings Sarcoma that overexpresses E-twenty-six (ETS), the method comprising administering a effective amount of 1-ethyl-7- (2-methyl-6- (1H-1,2,4-triazol-3-yl) pyridin-3-yl) -3,4-dihydropyrazine [2,3- b] Pyrazin-2 (1H) -one or a pharmaceutically acceptable salt, clathrate, solvate, stereoisomer, tautomer or isotopologist thereof to a patient who has Ewing's sarcoma that overexpresses STDs.1-etil-7-(2-metil-6-(1H-1,2,4-triazol-3-il)piridin-3-il)-3,4-dihidropirazino[2,3-b]pirazin-2(1H)-ona o una sal, clatrato, solvato, estereoisómero, tautómero o isotopólogo farmacéuticamente aceptable de los mismos para usar en un método para tratar el Sarcoma de Ewings que sobreexpresa E-twenty-six (ETS), comprendiendo el método administrar una cantidad efectiva de 1-etil-7-(2-metil-6-(1H-1,2,4-triazol-3-il)piridin-3-il)-3,4-dihidropirazino[2,3- b]pirazin-2(1H)-ona o una sal, clatrato, solvato, estereoisómero, tautómero o isotopólogo farmacéuticamente aceptable del mismo a un paciente que tiene sarcoma de Ewing que sobreexpresa ETS.
