PROBLEM TO BE SOLVED: To provide a fluorescent probe that has a high security to living organisms and that can exhibit a luminance large enough to be needed for bio-imaging.SOLUTION: There is provided a fluorescent probe which has an average aspect ratio in the range of 1.0-5.0, which is defined as a ratio (b/a) of a long diameter (b) to a short diameter (a) of particles and which includes crystalline graphene oxide fine particle and a target directional ligand which are covalently bonded to each other.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】生体に対する安全性が高く、しかもバイオイメージングに必要とされる程度に十分な輝度を示すことができる蛍光プローブを提供する。【解決手段】粒子の短径(a)に対する長径(b)の比の値(b/a)として定義されるアスペクト比の平均値が1.0~5.0であり、結晶性を有する酸化グラフェン微粒子に、標的指向性リガンドを共有結合を介して結合させて、蛍光プローブとする。【選択図】なし
