KLUGE, Michael,TESAR, Michael,FUCEK, Ivica,ELLWANGER, Kristina,REUSCH, Uwe,DAMRAT, Michael,RAJKOVIC, Erich,TREDER, Martin
申请号：
AU2019235433
公开号：
AU2019235433A1
申请日:
2019.03.14
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
Described are tetravalent, bispecific EGFR/CD16A antigen-binding proteins for engaging NK-cells towards EGFR-positive cells. EGFR/CD16A antigen-binding proteins with different pharmacokinetic (PK) properties are described. Further described is the use of bispecific EGFR/CD16A antigen-binding proteins for the treatment of an EGFR-positive malignancy, such as EGFR-positive tumors.
