#$%^&*AU2014203042A120140703.pdf#####METHODS FOR DIAGNOSIS AND INTERVENTION OF HEPATIC DISORDERS ABSTRACT The disclosure provides a method for quantification of hepatic function in a subject comprising measuring the clearance of an orally administered isotopically labeled cholic acid in a subject with, or suspected of having or developing, a hepatic disorder, for example, chronic hepatitis C. The disclosure further provides methods and kits for assessment of hepatic function.