A method of generating aircraft flight deck alerts is provided. An onboard alerting subsystem determines that an alert needs to be generated, and an onboard monitoring subsystem obtains a fatigue level of a flight crew member. An alert is generated with nominal audiovisual characteristics when the fatigue level is indicative of a non-fatigued physiological condition of the flight crew member, and with enhanced audiovisual characteristics when the fatigue level is indicative of a fatigued physiological condition. In addition, an automated flight crew training exercise can be launched when the flight crew member is fatigued, in an attempt to engage the flight crew member and alleviate fatigue.