Ustav Makromolekularni Chemie AV CR, v.v.i.;Univerzita Karlova v Praze, Prírodovedecká fakulta;Ustav organicke chemie a biochemie AV CR, v.v.i.
发明人:
申请号:
EP16706122.5
公开号:
EP3245514B1
申请日:
2016.01.13
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
Macromolecular water-soluble conjugates based on synthetic copolymers to which at least one affinity tag, at least one imaging probe, and at least one targeting ligand are bound via covalent bonds. The macromolecular conjugate may be used in identification, visualization, quantification or isolation of proteins and/or cells. The targeting ligand may be attached to the synthetic copolymer via a flexible linker.