The present invention provides a liquid medicine injection apparatus capable of injecting an additional fluid after completion of injection of a liquid medicine. The liquid medicine injection apparatus capable of injecting an additional fluid after completion of injection of a liquid medicine according to one embodiment of the present invention includes a cylinder elongated in a direction and having a nozzle formed at one end of the cylinder; a piston installed to be hermetically movable within the cylinder in the direction, wherein the piston defines a liquid medicine storage space to be filled with the liquid medicine introduced through the nozzle; an injector provided at the other end of the cylinder to allow the piston to be moved; a fluid tank for storing a fluid in a sealed state, wherein the fluid tank is disposed in the cylinder so as to be movable together with the piston and is deformable by a pressure; a needle unit disposed between the nozzle and the fluid tank, wherein the needle unit can penetrate a portion of the fluid tank to communicate the nozzle with the fluid tank; and a cap member provided between the needle unit and the fluid tank and deformable to allow the needle unit to penetrate the fluid tank.