NOVEL CD47 MONOCLONAL ANTIBODIES AND USES THEREOF

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专利权人:

I-Mab

发明人:

Zhengyi Wang,Lei Fang,Bingshi Guo,Jingwu Zang

申请号：

US15761309

公开号：

US20200140565A1

申请日:

2017.10.20

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention provides novel CD47 antibodies or immunologically active fragments thereof that have low immunogenicity in humans and cause low or no level of red blood cell depletion or hemagglutination, as well as pharmaceutical compositions containing such antibodies that can be used for treatment diseases mediated by CD47 or inhibition of phagocytosis or platelet aggregation.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/