Kirsten Damgaard Hoff,Jakob O. Gjørret,Kurt Pii,Sussie Steen Jensen,Henrik Winther
申请号：
US13001965
公开号：
US08685399B2
申请日:
2009.06.25
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to anti-human PAX 5 antibodies capable of binding to one or more epitopes located within the C-terminal regulatory domain of PAX 5. In particular the invention relates to an antibody, antigen binding fragment or recombinant protein thereof, which is capable of specific binding to an epitope located within the C-terminal fragment of human PAX 5 protein, wherein said epitope comprises from 3 to 17 amino acid residues of amino acid sequence GSPYYYSAAARGAAPPA (SEQ ID NO:2). The invention also relates to immunogenic peptide sequences for the production of the antibodies, diagnostic and therapeutic applications comprising using the antibodies and formulations comprising thereof.
