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Sugar chain added GLP-1 peptide
专利权人:
Yasuhiro Kajihara;Katsunari Tezuka;Kazuhiro Fukae;Takashi Tsuji;Izumi Sakamoto;Hiroaki Asai;Yuri Nambu
发明人:
Yasuhiro Kajihara,Takashi Tsuji,Izumi Sakamoto,Yuri Nambu,Kazuhiro Fukae,Katsunari Tezuka,Hiroaki Asai
申请号:
US13152082
公开号:
US08507429B2
申请日:
2011.06.02
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to an oligosaccharide chain added GLP-1 peptide that has higher stability in blood than that of GLP-1 and, preferably, exhibits higher activity of controlling blood-sugar levels than that of GLP-1. The present invention relates to an oligosaccharide chain added GLP-1 peptide having GLP-1 activity, wherein at least one amino acid is substituted with an oligosaccharide chain added amino acid, in: (a) GLP-1; (b) a peptide having the amino acid sequence of GLP-1 with deletion, substitution or addition of one or several amino acids; or (c) a GLP-1 analog.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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