A kind of reducible drug delivery device (1) is provided, including ontology (9,11), for receive cylindrantherae (8) cartridge-holder (7) and for by cartridge-holder (7) be releasably attached to ontology (9,11) or the device of dosing mechanism (13,14,17,18). Cartridge-holder (7) relative to ontology (9,11) or during the initial rotation connection movement of dosing mechanism, make cartridge-holder (7) relative to ontology (9,11) or dosing mechanism is moved along first axial direction, also, cartridge-holder (7) relative to ontology (9,11) or during the rotation of the continuation of dosing mechanism connection movement, move cartridge-holder (7) along the second opposite axial direction.
