Rama Abu Shmeis,Sheetal R. Muley,Xiaohong Shen,Zhixin Zong
申请号:
US14776287
公开号:
US09616030B2
申请日:
2014.03.14
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Disclosed in certain embodiments is a solid oral dosage form comprising a plurality of particles, each particle comprising (i) a core comprising an active agent susceptible to abuse and an internal adhesion promoter, wherein the cores are (i) dispersed in a matrix comprising a controlled release material or (ii) coated with a controlled release material. The dosage form can also include an alcohol resistant material.