Gillian Clark, legal representative;George M. Bright;Ross Graham Clark;Sam Liao
发明人:
Ross Graham Clark,George M. Bright,Sam Liao
申请号：
US11215746
公开号：
US08108149B2
申请日:
2005.08.29
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides standard deviation score (SDS) calculators, which SDS calculators are useful for transforming insulin-like growth factor-1 (IGF-1) concentrations to IGF-1 standard deviation scores. In one embodiment, IGF-1 blood levels are calculated so as to take into account IGFBP-3 blood levels (and, optionally, IGF-2 blood levels) to provide an IGF-1 production rate, which can be used to calculate an IGF-1 production rate SDS. The IGF-1 SDS and IGF-1 production rate SDS are particularly useful in assessing the stimulated rate of IGF-1 production in response to, for example, growth hormone therapy.
