An agent for virus inactivation capable of exhibiting inactivation action based on structural destruction such as degradation and decomposition against viruses, which comprises a monovalent copper compound such as cuprous oxide, cuprous sulfide, cuprous iodide, and cuprous chloride as an active ingredient, and a virus inactivation material, which contains the agent for virus inactivation on a surface of a substrate and/or inside of the substrate.本發明係有關可對病毒發揮變性及分解等構造上的破壞所伴隨之去活化作用之病毒去活化劑,其係含有氧化亞銅、硫化亞銅、碘化亞銅或氯化亞銅等一價銅化合物為有效成分之病毒去活化劑,以及於基材表面及/或內部含有該病毒去活化劑之病毒去活化材料。