A process for manufacture of sesame seed based bioactive peptides preferably based on Enzyme Membrane Reactor (EMR) based integrated process of sesame seed based synthesis of bioactive peptides and sesame glucosides. The sesame peptides and sesame glucosides produced have valuable therapeutic applications and the advancement is directed to an integrated process of peptide synthesis and glucosides isolation which is simple and cost- effective. Advantageously, the process of the present advancement presents good product quality and productivity.
