TREATMENT OF CANCER USING A SMAD3 INHIBITOR

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专利权人:

THE CHINESE UNIVERSITY OF HONG KONG

发明人:

LAN, HUI YAO

申请号：

EP13849415

公开号：

EP2911661A4

申请日:

2013.10.28

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The present invention resides in the discovery that Smad3, a key downstream mediator of TGF-² signaling, plays a critical role in development and progression of cancer. Thus, this application provides for a novel method of treating cancer by inhibiting Smad3 signaling, such as through administration of SIS3, an inhibitor of Smad3. Further provided are compositions and kits useful for treating cancer by way of inhibiting Smad3 signaling.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/