Larry L. Green,Qing Zhou,Bruce A. Keyt,Xiao-Dong Yang,Stephen Charles Emery,David Charles Blakey
申请号：
US14486050
公开号：
US10066011B2
申请日:
2014.09.15
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Antibodies directed to the antigen Ang-2 and uses of such antibodies are described. In particular, fully human monoclonal antibodies directed to the antigen Ang-2. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies.
