THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;UNIVERSITY OF WASHINGTON
发明人:
Daniel Adriano Silva Manzano,Shawn Yu,Umut Ulge,David Baker,Kenan Christopher Garcia,Jamie Spangler,Carl Walkey
申请号:
US16572038
公开号:
US10703791B2
申请日:
2019.09.16
申请国别(地区):
US
年份:
2020
代理人:
摘要:
De novo designed polypeptides that bind to IL-2 receptor βγc heterodimer (IL-2Rβγc), IL-4 receptor αγc heterodimer (IL-4Rαγc), or IL-13 receptor α subunit (IL-13Rα) are disclosed, as are methods for using and designing the polypeptides.