Margie A. Hunt,Joseph Owen Deasy,Reza Farjam,Aditya Apte,Neelam Tyagi,Harini Veeraraghavan,Kristen L. Zakian
申请号：
US16348181
公开号：
US20190365335A1
申请日:
2017.11.10
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Described herein are systems and methods for synthetic CT image creation that allow MR-only radiotherapy of cancer patients, e.g., head and neck (H&；N) cancer patients, prostate cancer patients, patients with cancer of the pelvis, abdomen cancer patients, patients with cancer of the extremities, brain cancer patients, or thorax cancer patients. The methods and systems described herein feature image processing techniques that improve the similarity between CT and MR images prior to CT-MR image registration, as well as standardization of the MR intensity histograms prior to MR-MR registration. Application of the techniques result in more accurate assignment of the Hounsfield unit to each point in the synthetic CT compared to other atlas-based methods, providing for more accurate dosing in MR-only radiotherapy simulation and planning.
