PROCÉDÉS DE TRAITEMENT DE L'OSTÉONÉCROSE AVEC DES COMPOSÉS DE LLP2A-BISPHOSPHONATE

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专利权人:

The Regents of the University of California

发明人:

LANE, Nancy,YAO, Wei

申请号：

EP17739064

公开号：

EP3402803A4

申请日:

2017.01.13

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Methods of treating osteonecrosis in a subject are provided. In some embodiments, the method comprises administering to a subject having or suspected of having osteonecrosis a pharmaceutical composition comprising a conjugate of an LLP2A peptidomimetic ligand and a bisphosphonate drug. In some embodiments, the pharmaceutical composition comprises a conjugate of LLP2A and alendronate (LLP2A-Ale). In some embodiments, the method further comprises administering exogenous mesenchymal stem cells.

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中国工程科技知识中心

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http://www.ckcest.cn/home/