Bertrand L. Chenard;Manuka Ghosh;Charles A. Blum;Scott M. Capitosti;Rajagopal Bakthavatchalam;Jianjun Xu
发明人:
Rajagopal Bakthavatchalam,Scott M. Capitosti,Jianjun Xu,Bertrand L. Chenard,Manuka Ghosh,Charles A. Blum
申请号:
US13215195
公开号:
US20120208829A1
申请日:
2011.08.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
2-Phenoxy pyrimidinone analogues are provided, of the Formula:wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.