YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM
发明人:
YEDGAR, Saul
申请号：
AU2014200908
公开号：
AU2014200908A1
申请日:
2014.02.21
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
#$%^&*AU2014200908A120140313.pdf#####ABSTRACT A compound represented by the structure of the general formula (A): L- Z-Y-- X -~- n 5 (A) wherein L is a lipid or a phospholipid Z is either nothing, ethanolamine, serine, inositol, choline, or glycerol Y is either nothing or a spacer group ranging in length from 2 to 30 atoms 10 X is a physiologically acceptable monomer, dimer, oligomer, or polymer and n is a number from I to 1000. 5136530_1 (GHMatters) P75827.AU.21/22 Fig. 1.1: Inhibition of endothelin-1 (ET)-induced contraction of rat tracheal rings by Lipid-conjugates. A: Contraction of rat trachea by Endothelin-1. 100 75 50 25 0 .9 -8 -7 *6 -5 -4 L-ogIET] B: Effect of HYPE on ETinduced contraction of rat 100 trachea. 80 60 40 20 0 0.0 0.5 1,0 1.5 2.0 2.5 3.0 3.5 ITYPE M]
