A universal self-locking anatomical plate for posterior of acetabulum and pelvis, which includes a right plate (1), a plurality of screws (2) and a guiding sleeve (3). The right plate (1) includes a region-a, a region-b, a region-c, a region-d and a region-e, which can respectively fix a certain region of an acetabulum, the region-a is provided thereon with three first locking holes for receiving the locking screws, the region-b is provided thereon with at least two second locking holes, the region-c is provided thereon with two positioning holes and twelve third locking holes, the region-d is provided thereon with three fourth locking holes, and the region-e is provided thereon with one fifth locking hole. The plate has an optimized structure, and has three capabilities: good safety, good stability, and biomechanic matching. Additionally, the fitness of the plate to the surface of the acetabulum mode is good.