Способ индивидуального подбора энергетических параметров микроимпульсного режима на лазере Navilas 577s для лечения центральной серозной хориоретинопатии
Federalnoe gosudarstvennoe avtonomnoe uchrezhdenie "Natsionalnyj meditsinskij issledovatelskij tsentr "Mezhotraslevoj nauchno-tekhnicheskij kompleks "Mikrokhirurgiya glaza" imeni akademika S.N. Fedoro
发明人:
Volodin Pavel Lvovich (RU),Володин Павел Львович (RU),Ivanova Elena Vladimirovna (RU),Иванова Елена Владимировна (RU)
申请号：
RU2018115916
公开号：
RU0002669858C1
申请日:
2018.04.27
申请国别(地区):
RU
年份:
2018
代理人:
摘要：
FIELD: medicine.SUBSTANCE: invention relates to the field of medicine, namely, to ophthalmology, and can be used for the treatment of central serous chorioretinopathy (CSChRP). Optical coherence tomography (OCT) with En Face mode and fluorescent angiography (FAG) are performed to identify defects and retinal pigment epithelium (RPE) defects that correspond to filtration points. Make a color photograph of the fundus with the Navilas 577s navigational laser unit (NLU). Using the NLU Navilas 577s software, superimpose the OCT and/or FAG data on a color photograph of the fundus and completely compare them. Select a pattern in the software of the NL Navilas 577s from one or more applicators, close to each other, and arrange them so as to fully cover the defects and detachments of the RPE corresponding to the filtration points. To determine the individual energy parameters required for treatment, computer simulation is preliminarily carried out by numerically solving the heat equation with an estimate of the proportion of denatured protein, by the result of which the energy parameters are determined from the range of the selective and effective micropulse regime realized on the NL Navilas 577s: duration of the micropulse is 50 mcs, interval between pulses is 2,000 mcs, duty cycle is 2.4 %, duration of the packet is 10 ms, number of pulses in the packet is 5, spot diameter is 100 mcm, power is 0.4 to 1.9 W, wavelength is 577 nm. Power is selected for each patient individually, depending on the degree of pigmentation of the fundus and transparency of optical media by testing and applying three appliqués of each power in steps of 0.1 W to an intact retina in the region of the upper or lower vascular arcade. With transparent optical media and pronounced pigmentation, testing is performed with a power in the range from 0.4 to 1.2 W, with transparent optical media and medium pigmentation – from 0.8 to 1.6 W, with transparent optical media and a weak degree of pigmentation – fro
